Supplements: Science Backed Longevity

Aging is an inevitable part of life; however, ongoing scientific research continually uncovers ways to slow its effects, enabling us to thrive in our later years through scientifically backed methods. Among these discoveries are supplements that, when used in conjunction with a healthy lifestyle, have shown promise in promoting longevity and well-being. Here are some of the top supplements that have stood up to scientific scrutiny.

1. Omega-3 Fatty Acids

Noticeable Effects: Improved heart health and cognitive function.

Recommended Dose: 1,000-2,000 mg daily.

Priority: High - essential for overall health.

Risks: May interact with blood-thinning medications.

Benefits: Omega-3s are vital for maintaining heart health, reducing inflammation, and supporting brain function. Clinical trials have consistently demonstrated their cardiovascular benefits 1.

2. Vitamin D3

Noticeable Effects: Enhanced immune function and bone health.

Recommended Dose: 800-2,000 IU daily, depending on individual needs.

Priority: High - many people are deficient.

Risks: Vitamin D toxicity can occur with excessive doses.

Benefits: Vitamin D is crucial for bone density, immune health, and has been linked to a lower risk of several diseases. Its importance is underscored by widespread deficiency 2.

3. Coenzyme Q10 (CoQ10)

Noticeable Effects: Increased energy levels and improved heart health.

Recommended Dose: 100-200 mg daily.

Priority: Medium - especially for those with cardiovascular concerns.

Risks: Can lower blood sugar levels; caution is advised for those with diabetes.

Benefits: CoQ10 is an antioxidant that helps cells produce energy and has been shown to benefit heart health in clinical studies 3.

4. Curcumin

Noticeable Effects: May reduce inflammation and oxidative stress.

Recommended Dose: 500-2,000 mg of turmeric extract daily, standardized to 95% curcuminoids.

Priority: Medium - for its anti-inflammatory and antioxidant properties.

Risks: High doses can cause gastrointestinal issues.

Benefits: The active ingredient in turmeric, curcumin has been studied for its anti-inflammatory effects and potential to improve symptoms of depression and arthritis 4.

5. Resveratrol

Noticeable Effects: Potential improvement in heart health and longevity.

Recommended Dose: 150-500 mg daily.

Priority: Low - can be obtained through diet.

Risks: Limited data on long-term use.

Benefits: Resveratrol, found in grapes and berries, has been researched for its anti-aging properties and its ability to mimic the effects of calorie restriction.

6. Green Tea Extract (EGCG)

Noticeable Effects: Antioxidant and metabolic benefits.

Recommended Dose: 250–500 mg daily.

Priority: Medium - if seeking metabolic and antioxidant support.

Risks: Excessive intake can lead to liver issues.

Benefits: EGCG, the active compound in green tea, has been associated with a reduced risk of certain cancers and heart disease, and may aid in weight management.

7. Nicotinamide Riboside (NR)

Noticeable Effects: May increase cellular energy and vitality.

Recommended Dose: 300 mg daily.

Priority: Medium - emerging research on aging.

Risks: Generally well-tolerated, but more research is needed.

Benefits: NR is a form of vitamin B3 that has been shown to boost levels of NAD+, a molecule essential for energy metabolism and cell health, which may have anti-aging effects.

When incorporating supplements into your routine, it’s crucial to consult with a healthcare provider to ensure they’re appropriate for your individual health needs and circumstances. Remember, supplements are most effective when used as part of a holistic approach to health that includes a balanced diet and regular physical activity.

Here are the best food sources for each of the supplements mentioned:

1. Omega-3 Fatty Acids

• Fatty fish like mackerel, salmon, and cod liver oil 1.

• Nuts and seeds such as flaxseeds, chia seeds, and walnuts 2.

1. Vitamin D

• Fatty fish such as salmon, herring, and mackerel 3.

• Fortified foods like milk, orange juice, and cereals 3.

• Sun-exposed mushrooms 3.

1. Coenzyme Q10 (CoQ10)

• Organ meats like liver and kidney 4.

• Fatty fish including salmon and mackerel 4.

• Whole grains, nuts, and soybeans 5.

1. Curcumin

• Turmeric is the primary source of curcumin 6.

• Other sources include ginger and curry powder 7.

1. Resveratrol

• Grapes 8.

• Peanuts, berries, and cocoa 9.

1. Green Tea Extract (EGCG)

• Green tea is the most potent source 10.

• Other teas like white, oolong, and black teas also contain EGCG in smaller amounts 11.

1. Nicotinamide Riboside (NR)

• Dairy milk is a known source of NR 12.

• Yeast-containing products like bread may also contain NR 13.

These foods can help you naturally increase your intake of these beneficial compounds. However, it’s important to note that the concentration of these compounds in food sources can vary, and in some cases, supplements may be necessary to achieve therapeutic doses.

This post is based on current scientific research available as of 2024 and is not intended as medical advice. For personalized recommendations, please consult a healthcare professional.

1: “Omega-3 Fatty Acids: An Essential Contribution.” Harvard T.H. Chan School of Public Health. 2: “Vitamin D: Fact Sheet for Health Professionals.” National Institutes of Health. 3: “Coenzyme Q10.” Mayo Clinic. 4: “Curcumin: A Review of Its’ Effects on Human Health.” Journal of Medicinal Food. : “Resveratrol in Cardiovascular Health and Disease.” Cardiology in Review. : “Green Tea Catechins: Their Use in Treating and Preventing Infectious Diseases.” BioMed Research International. : “NAD+ and Vitamin B3: From Metabolism to Therapies.” Journal of Pharmacology and Experimental Therapeutics.